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Live Vaccination Generates Both Disease Tolerance and Host Resistance During Chronic Pulmonary Infection With Highly Virulent Francisella tularensis SchuS4

Disease tolerance can preserve host homeostasis and limit the negative impact of infections. We report that vaccinated mice survived pulmonary challenge with the extremely virulent SchuS4 strain of Francisella tularensis for at least 100 days, despite the persistence of large numbers (~10(4)) of org...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Soucy, Alicia M, Hurteau, Gregory J, Metzger, Dennis W
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195663/
https://ncbi.nlm.nih.gov/pubmed/29931113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy379
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