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Gain-of-Function Mutations in the Phospholipid Flippase MprF Confer Specific Daptomycin Resistance
Daptomycin, a calcium-dependent lipopeptide antibiotic whose full mode of action is still not entirely understood, has become a standard-of-care agent for treating methicillin-resistant Staphylococcus aureus (MRSA) infections. Daptomycin-resistant (DAP-R) S. aureus mutants emerge during therapy, fea...
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| 出版年: | mBio |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6299216/ https://ncbi.nlm.nih.gov/pubmed/30563904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01659-18 |
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