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Causal Role of Single Nucleotide Polymorphisms within the mprF Gene of Staphylococcus aureus in Daptomycin Resistance

Single nucleotide polymorphisms (SNPs) within the mprF open reading frame (ORF) have been commonly observed in daptomycin-resistant (DAP(r)) Staphylococcus aureus strains. Such SNPs are usually associated with a gain-in-function phenotype, in terms of either increased synthesis or enhanced transloca...

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Detalhes bibliográficos
Main Authors: Yang, Soo-Jin, Mishra, Nagendra N., Rubio, Aileen, Bayer, Arnold S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811309/
https://ncbi.nlm.nih.gov/pubmed/24002096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01184-13
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