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Diminished phosphorylation of CREB is a key event in the dysregulation of gluconeogenesis and glycogenolysis in PCB126 hepatotoxicity

The dioxin-like PCB126 elicits toxicity in various target organs. In rat liver an alteration in the transcript levels of several genes involved in glucose and fatty acid metabolism provides insights into the origin of its hepatotoxicity. To explore these, male Sprague-Dawley rats, fed AIN-93G diet w...

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Publicado en:Chem Res Toxicol
Main Authors: Gadupudi, Gopi S, Klingelhutz, Aloysius J, Robertson, Larry W
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298789/
https://ncbi.nlm.nih.gov/pubmed/27509375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.6b00172
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