N-acetylcysteine (NAC) diminishes the severity of PCB 126 – induced fatty liver in male rodents

Potent aryl hydrocarbon receptor agonists like PCB 126 (3,3′,4,4′,5-pentachlorobiphenyl) cause oxidative stress and liver pathology, including fatty liver. Our question was whether dietary supplementation with N-acetylcysteine (NAC), an antioxidant, can prevent these adverse changes. Male Sprague-Da...

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Detalhes bibliográficos
Main Authors: Lai, Ian K., Dhakal, Kiran, Gadupudi, Gopi S, Li, Miao, Ludewig, Gabriele, Robertson, Larry W., Olivier, Alicia K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438370/
https://ncbi.nlm.nih.gov/pubmed/22824115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2012.07.007
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