PCB126-Induced Disruption in Gluconeogenesis and Fatty Acid Oxidation Precedes Fatty Liver in Male Rats

3,3′,4,4′,5-Pentachlorobiphenyl (PCB126), a dioxin-like polychlorinated biphenyl (PCB) and a potent aryl hydrocarbon receptor (AhR) agonist, is implicated in the disruption of both carbohydrate and lipid metabolism which ultimately leads to wasting disorders, metabolic disease, and nonalcoholic fatt...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Gadupudi, Gopi S., Klaren, William D., Olivier, Alicia K., Klingelhutz, Aloysius J., Robertson, Larry W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Mechanisms of PCB-Induced Fatty Liver
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731404/
https://ncbi.nlm.nih.gov/pubmed/26396156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv215
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