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Tissue-specific emergence of regulatory and intraepithelial T cells from a clonal T cell precursor

Peripheral Foxp3(+) regulatory T cells (pT(regs)) maintain immune homeostasis by controlling potentially harmful effector T cell responses toward dietary and microbial antigens. Although the identity of the T cell receptor (TCR) can impose commitment and functional specialization of T cells, less is...

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Dettagli Bibliografici
Pubblicato in:Sci Immunol
Autori principali: Bilate, Angelina M., Bousbaine, Djenet, Mesin, Luka, Agudelo, Marianna, Leube, Justin, Kratzert, Andreas, Dougan, Stephanie K., Victora, Gabriel D., Ploegh, Hidde L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296461/
https://ncbi.nlm.nih.gov/pubmed/28783695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aaf7471
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