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T cell receptor is required for differentiation but not maintenance of intestinal CD4(+) intraepithelial lymphocytes

The gut epithelium is populated by intraepithelial lymphocytes (IELs), a heterogeneous T cell population with cytotoxic and regulatory properties, which can be acquired at the epithelial layer. However, the role of T cell receptor (TCR) in this process remains unclear. Single-cell transcriptomic ana...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Immunity
Prif Awduron: Bilate, Angelina M., London, Mariya, Castro, Tiago B. R., Mesin, Luka, Bortolatto, Juliana, Kongthong, Suppawat, Harnagel, Audrey, Victora, Gabriel D., Mucida, Daniel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7677182/
https://ncbi.nlm.nih.gov/pubmed/33022229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.09.003
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