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LILRB4 signaling in leukemia cells mediates T cell suppression and tumor infiltration
Immune checkpoint blockade therapy has been successful in treating some types of cancers but has not shown clinical benefits for treating leukemia (1). This result suggests that leukemia exploits unique escape mechanisms. Certain immune inhibitory receptors that are expressed by normal immune cells...
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| Gepubliceerd in: | Nature |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6296374/ https://ncbi.nlm.nih.gov/pubmed/30333625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0615-z |
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