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LILRB4 ITIMs mediate the T cell suppression and infiltration of acute myeloid leukemia cells
We recently demonstrated that leukocyte Ig-like receptor 4 (LILRB4) expressed by monocytic acute myeloid leukemia (AML) cells mediates T-cell inhibition and leukemia cell infiltration via its intracellular domain. The cytoplasmic domain of LILRB4 contains three immunoreceptor tyrosine-based inhibito...
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| Publicado no: | Cell Mol Immunol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7052276/ https://ncbi.nlm.nih.gov/pubmed/31700117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0321-2 |
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