Antagonistic anti-LILRB1 monoclonal antibody regulates antitumor functions of natural killer cells

BACKGROUND: Current immune checkpoint blockade strategies have been successful in treating certain types of solid cancer. However, checkpoint blockade monotherapies have not been successful against most hematological malignancies including multiple myeloma and leukemia. There is an urgent need to id...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Chen, Heyu, Chen, Yuanzhi, Deng, Mi, John, Samuel, Gui, Xun, Kansagra, Ankit, Chen, Weina, Kim, Jaehyup, Lewis, Cheryl, Wu, Guojin, Xie, Jingjing, Zhang, Lingbo, Huang, Ryan, Liu, Xiaoye, Arase, Hisashi, Huang, Yang, Yu, Hai, Luo, Wenxin, Xia, Ningshao, Zhang, Ningyan, An, Zhiqiang, Zhang, Cheng Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Basic Tumor Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418854/
https://ncbi.nlm.nih.gov/pubmed/32771992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000515
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