Control of epigenetic states by WT1 via regulation of de novo DNA methyltransferase 3A

Although tumour suppressor gene hypermethylation is a universal feature of cancer cells, little is known about the necessary molecular triggers. Here, we show that Wilms' tumour 1 (WT1), a developmental master regulator that can also act as a tumour suppressor or oncoprotein, transcriptionally...

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Publicado en:Hum Mol Genet
Autores principales: Szemes, Marianna, Dallosso, Anthony R., Melegh, Zsombor, Curry, Thomas, Li, Yifan, Rivers, Caroline, Uney, James, Mägdefrau, Ann-Sophie, Schwiderski, Karolin, Park, Ji H., Brown, Keith W., Shandilya, Jayasha, Roberts, Stefan G. E., Malik, Karim
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2013
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296327/
https://ncbi.nlm.nih.gov/pubmed/23042785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds403
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