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Structure and role for active site lid of lactate monooxygenase from Mycobacterium smegmatis

Lactate monooxygenase (LMO) catalyzes the FMN‐dependent “coupled” oxidation of lactate and O(2) to acetate, carbon dioxide, and water, involving pyruvate and hydrogen peroxide as enzyme‐bound intermediates. Other α‐hydroxy acid oxidase family members follow an “uncoupled pathway,” wherein the α‐keto...

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Detalles Bibliográficos
Publicado en:Protein Sci
Main Authors: Kean, Kelsey M., Karplus, P. Andrew
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Inc. 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295902/
https://ncbi.nlm.nih.gov/pubmed/30207005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3506
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