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Structure and role for active site lid of lactate monooxygenase from Mycobacterium smegmatis

Lactate monooxygenase (LMO) catalyzes the FMN‐dependent “coupled” oxidation of lactate and O(2) to acetate, carbon dioxide, and water, involving pyruvate and hydrogen peroxide as enzyme‐bound intermediates. Other α‐hydroxy acid oxidase family members follow an “uncoupled pathway,” wherein the α‐keto...

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Bibliografiske detaljer
Udgivet i:Protein Sci
Main Authors: Kean, Kelsey M., Karplus, P. Andrew
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295902/
https://ncbi.nlm.nih.gov/pubmed/30207005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3506
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