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Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD
The dihydroorotase (DHOase) domain of the multifunctional protein carbamoyl-phosphate synthetase 2, aspartate transcarbamoylase, and dihydroorotase (CAD) catalyzes the third step in the de novo biosynthesis of pyrimidine nucleotides in animals. The crystal structure of the DHOase domain of human CAD...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6295737/ https://ncbi.nlm.nih.gov/pubmed/30315107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005494 |
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