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Class matters: Sensitivity of BRAF-mutant melanoma to MAPK inhibition
Mutations in BRAF outside of the 600 codon (BRAF non-V600) occur across cancer types, including in 3-5% of melanomas. The optimal treatment strategies are not clear, but could include MEK inhibitors based on pre-clinical studies. Combining BRAF and MEK inhibitors in this population may provide addit...
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| Publicat a: | Clin Cancer Res |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6295213/ https://ncbi.nlm.nih.gov/pubmed/30042206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-1795 |
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