SUMOylation of PCNA by PIAS1 and PIAS4 promotes template switch in the chicken and human B cell lines

DNA damage tolerance (DDT) releases replication blockage caused by damaged nucleotides on template strands employing two alternative pathways, error-prone translesion DNA synthesis (TLS) and error-free template switch (TS). Lys164 of proliferating cell nuclear antigen (PCNA) is SUMOylated during the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Mohiuddin, Mohiuddin, Evans, Terry John, Rahman, Md Maminur, Keka, Islam Shamima, Tsuda, Masataka, Sasanuma, Hiroyuki, Takeda, Shunichi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2018
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294928/
https://ncbi.nlm.nih.gov/pubmed/30487218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716349115
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