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SUMOylation of PCNA by PIAS1 and PIAS4 promotes template switch in the chicken and human B cell lines

DNA damage tolerance (DDT) releases replication blockage caused by damaged nucleotides on template strands employing two alternative pathways, error-prone translesion DNA synthesis (TLS) and error-free template switch (TS). Lys164 of proliferating cell nuclear antigen (PCNA) is SUMOylated during the...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Mohiuddin, Mohiuddin, Evans, Terry John, Rahman, Md Maminur, Keka, Islam Shamima, Tsuda, Masataka, Sasanuma, Hiroyuki, Takeda, Shunichi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294928/
https://ncbi.nlm.nih.gov/pubmed/30487218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716349115
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