Antidepressants act by inducing autophagy controlled by sphingomyelin–ceramide

Major depressive disorder (MDD) is a common and severe disease characterized by mood changes, somatic alterations, and often suicide. MDD is treated with antidepressants, but the molecular mechanism of their action is unknown. We found that widely used antidepressants such as amitriptyline and fluox...

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Publicat a:Mol Psychiatry
Autors principals: Gulbins, Anne, Schumacher, Fabian, Becker, Katrin Anne, Wilker, Barbara, Soddemann, Matthias, Boldrin, Francesco, Müller, Christian P., Edwards, Michael J., Goodman, Michael, Caldwell, Charles C., Kleuser, Burkhard, Kornhuber, Johannes, Szabo, Ildiko, Gulbins, Erich
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294742/
https://ncbi.nlm.nih.gov/pubmed/30038230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0090-9
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