Antidepressants act by inducing autophagy controlled by sphingomyelin–ceramide

Major depressive disorder (MDD) is a common and severe disease characterized by mood changes, somatic alterations, and often suicide. MDD is treated with antidepressants, but the molecular mechanism of their action is unknown. We found that widely used antidepressants such as amitriptyline and fluox...

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Gepubliceerd in:Mol Psychiatry
Hoofdauteurs: Gulbins, Anne, Schumacher, Fabian, Becker, Katrin Anne, Wilker, Barbara, Soddemann, Matthias, Boldrin, Francesco, Müller, Christian P., Edwards, Michael J., Goodman, Michael, Caldwell, Charles C., Kleuser, Burkhard, Kornhuber, Johannes, Szabo, Ildiko, Gulbins, Erich
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294742/
https://ncbi.nlm.nih.gov/pubmed/30038230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0090-9
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