Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein

Eastern equine encephalitis virus (EEEV) is a mosquito-transmitted alphavirus with a high case mortality rate in humans. EEEV is a biodefense concern because of its potential for aerosol spread and the lack of existing countermeasures. In this study, we identified a panel of 18 neutralizing murine m...

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Detalhes bibliográficos
Publicado no:Nat Microbiol
Main Authors: Kim, Arthur S., Austin, S. Kyle, Gardner, Christina L., Zuiani, Adam, Reed, Douglas S., Trobaugh, Derek W., Sun, Chengqun, Basore, Katherine, Williamson, Lauren E., Crowe, James E., Slifka, Mark K., Fremont, Daved H., Klimstra, William B., Diamond, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294662/
https://ncbi.nlm.nih.gov/pubmed/30455470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-018-0286-4
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