Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein

Eastern equine encephalitis virus (EEEV) is a mosquito-transmitted alphavirus with a high case mortality rate in humans. EEEV is a biodefense concern because of its potential for aerosol spread and the lack of existing countermeasures. In this study, we identified a panel of 18 neutralizing murine m...

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Publicat a:Nat Microbiol
Autors principals: Kim, Arthur S., Austin, S. Kyle, Gardner, Christina L., Zuiani, Adam, Reed, Douglas S., Trobaugh, Derek W., Sun, Chengqun, Basore, Katherine, Williamson, Lauren E., Crowe, James E., Slifka, Mark K., Fremont, Daved H., Klimstra, William B., Diamond, Michael S.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294662/
https://ncbi.nlm.nih.gov/pubmed/30455470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-018-0286-4
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