Cooperativity between the 3’ untranslated region microRNA binding sites is critical for the virulence of eastern equine encephalitis virus

Eastern equine encephalitis virus (EEEV), a mosquito-borne RNA virus, is one of the most acutely virulent viruses endemic to the Americas, causing between 30% and 70% mortality in symptomatic human cases. A major factor in the virulence of EEEV is the presence of four binding sites for the hematopoi...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Trobaugh, Derek W., Sun, Chengqun, Bhalla, Nishank, Gardner, Christina L., Dunn, Matthew D., Klimstra, William B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936876/
https://ncbi.nlm.nih.gov/pubmed/31658290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007867
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