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Conditional genome engineering reveals canonical and divergent roles for the Hus1 component of the 9–1–1 complex in the maintenance of the plastic genome of Leishmania

Leishmania species are protozoan parasites whose remarkably plastic genome limits the establishment of effective genetic manipulation and leishmaniasis treatment. The strategies used by Leishmania to maintain its genome while allowing variability are not fully understood. Here, we used DiCre-mediate...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Damasceno, Jeziel D, Obonaga, Ricardo, Silva, Gabriel L A, Reis-Cunha, João L, Duncan, Samuel M, Bartholomeu, Daniella C, Mottram, Jeremy C, McCulloch, Richard, Tosi, Luiz R O
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294564/
https://ncbi.nlm.nih.gov/pubmed/30380080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1017
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