Conditional knockout of RAD51-related genes in Leishmania major reveals a critical role for homologous recombination during genome replication

Homologous recombination (HR) has an intimate relationship with genome replication, both during repair of DNA lesions that might prevent DNA synthesis and in tackling stalls to the replication fork. Recent studies led us to ask if HR might have a more central role in replicating the genome of Leishm...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Damasceno, Jeziel D., Reis-Cunha, João, Crouch, Kathryn, Beraldi, Dario, Lapsley, Craig, Tosi, Luiz R. O., Bartholomeu, Daniella, McCulloch, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360064/
https://ncbi.nlm.nih.gov/pubmed/32609721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008828
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