Structural and functional insight into serine hydroxymethyltransferase from Helicobacter pylori

Serine hydroxymethyltransferase (SHMT), encoded by the glyA gene, is a ubiquitous pyridoxal 5’-phosphate (PLP)-dependent enzyme that catalyzes the formation of glycine from serine. The thereby generated 5,10-methylene tetrahydrofolate (MTHF) is a major source of cellular one-carbon units and a key i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sodolescu, Andreea, Dian, Cyril, Terradot, Laurent, Bouzhir-Sima, Latifa, Lestini, Roxane, Myllykallio, Hannu, Skouloubris, Stéphane, Liebl, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294363/
https://ncbi.nlm.nih.gov/pubmed/30550583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208850
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