Structural insights into Helicobacter pylori oncoprotein CagA interaction with β1 integrin

Infection with the gastric pathogen Helicobacter pylori is a risk factor for the development of gastric cancer. Pathogenic strains of H. pylori carry a type IV secretion system (T4SS) responsible for the injection of the oncoprotein CagA into host cells. H. pylori and its cag-T4SS exploit α5β1 integ...

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Detalhes bibliográficos
Main Authors: Kaplan-Türköz, Burcu, Jiménez-Soto, Luisa F., Dian, Cyril, Ertl, Claudia, Remaut, Han, Louche, Arthur, Tosi, Tommaso, Haas, Rainer, Terradot, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437852/
https://ncbi.nlm.nih.gov/pubmed/22908298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206098109
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