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Flavin-dependent thymidylate synthase X limits chromosomal DNA replication
We have investigated the hitherto unexplored possibility that differences in the catalytic efficiencies of thymidylate synthases ThyX and ThyA, enzymes that produce the essential DNA precursor dTMP, have influenced prokaryotic genome evolution. We demonstrate that DNA replication speed in bacteria a...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2481370/ https://ncbi.nlm.nih.gov/pubmed/18621705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801356105 |
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