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Conservation and Role of Electrostatics in Thymidylate Synthase

Conservation of function across families of orthologous enzymes is generally accompanied by conservation of their active site electrostatic potentials. To study the electrostatic conservation in the highly conserved essential enzyme, thymidylate synthase (TS), we conducted a systematic species-based...

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Vydáno v:Sci Rep
Hlavní autoři: Garg, Divita, Skouloubris, Stephane, Briffotaux, Julien, Myllykallio, Hannu, Wade, Rebecca C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661567/
https://ncbi.nlm.nih.gov/pubmed/26612036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17356
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