Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals

BACKGROUND: Metformin is a widely prescribed antihyperglycemic agent that has been also associated with multiple therapeutic effects in various diseases, including several types of malignancies. There is growing evidence regarding the contribution of the epigenetic mechanisms in reaching metformin’s...

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Detaylı Bibliyografya
Yayımlandı:Clin Epigenetics
Asıl Yazarlar: Elbere, Ilze, Silamikelis, Ivars, Ustinova, Monta, Kalnina, Ineta, Zaharenko, Linda, Peculis, Raitis, Konrade, Ilze, Ciuculete, Diana Maria, Zhukovsky, Christina, Gudra, Dita, Radovica-Spalvina, Ilze, Fridmanis, Davids, Pirags, Valdis, Schiöth, Helgi B., Klovins, Janis
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2018
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293577/
https://ncbi.nlm.nih.gov/pubmed/30545422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0593-x
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