Association of metformin administration with gut microbiome dysbiosis in healthy volunteers

BACKGROUND: Metformin is a widely used first-line drug for treatment of type 2 diabetes. Despite its advantages, metformin has variable therapeutic effects, contraindications, and side effects. Here, for the very first time, we investigate the short-term effect of metformin on the composition of hea...

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Bibliographic Details
Published in:PLoS One
Main Authors: Elbere, Ilze, Kalnina, Ineta, Silamikelis, Ivars, Konrade, Ilze, Zaharenko, Linda, Sekace, Kristine, Radovica-Spalvina, Ilze, Fridmanis, Davids, Gudra, Dita, Pirags, Valdis, Klovins, Janis
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160085/
https://ncbi.nlm.nih.gov/pubmed/30261008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204317
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