Whole-blood transcriptome profiling reveals signatures of metformin and its therapeutic response

Metformin, a biguanide agent, is the first-line treatment for type 2 diabetes mellitus due to its glucose-lowering effect. Despite its wide application in the treatment of multiple health conditions, the glycemic response to metformin is highly variable, emphasizing the need for reliable biomarkers....

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Gepubliceerd in:PLoS One
Hoofdauteurs: Ustinova, Monta, Ansone, Laura, Silamikelis, Ivars, Rovite, Vita, Elbere, Ilze, Silamikele, Laila, Kalnina, Ineta, Fridmanis, Davids, Sokolovska, Jelizaveta, Konrade, Ilze, Pirags, Valdis, Klovins, Janis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418999/
https://ncbi.nlm.nih.gov/pubmed/32780768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237400
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