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Plasma and urinary p21: potential biomarkers of AKI and renal aging

p21 is upregulated in renal tubules in response to acute kidney injury (AKI). and localizes in the nucleus, where it induces cell cycle arrest (CCA). These events can mitigate early injury but can also facilitate the onset of the degenerative cell senescence/“aging” process. Hence, we asked the foll...

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Veröffentlicht in:Am J Physiol Renal Physiol
Hauptverfasser: Johnson, Ali C., Zager, Richard A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293288/
https://ncbi.nlm.nih.gov/pubmed/30066587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00328.2018
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