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Plasma and urinary p21: potential biomarkers of AKI and renal aging

p21 is upregulated in renal tubules in response to acute kidney injury (AKI). and localizes in the nucleus, where it induces cell cycle arrest (CCA). These events can mitigate early injury but can also facilitate the onset of the degenerative cell senescence/“aging” process. Hence, we asked the foll...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Renal Physiol
Main Authors: Johnson, Ali C., Zager, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293288/
https://ncbi.nlm.nih.gov/pubmed/30066587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00328.2018
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