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MDM2 inhibitor ameliorates cisplatin‐induced nephropathy via NFκΒ signal inhibition
Cisplatin is a platinum‐containing chemotherapeutic drug, which is widely used and highly effective. While effective against tumors, its use is limited by severe side effects such as nephrotoxicity and bone marrow suppression. Murine double minute 2 (MDM2) is the E3 ubiquitin ligase of the tumor sup...
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| Publicado no: | Pharmacol Res Perspect |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6293176/ https://ncbi.nlm.nih.gov/pubmed/30564368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.450 |
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