MDM2 inhibitor ameliorates cisplatin‐induced nephropathy via NFκΒ signal inhibition

Cisplatin is a platinum‐containing chemotherapeutic drug, which is widely used and highly effective. While effective against tumors, its use is limited by severe side effects such as nephrotoxicity and bone marrow suppression. Murine double minute 2 (MDM2) is the E3 ubiquitin ligase of the tumor sup...

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Detaylı Bibliyografya
Yayımlandı:Pharmacol Res Perspect
Asıl Yazarlar: Fujikura, Tomoyuki, Yasuda, Hideo, Iwakura, Takamasa, Tsuji, Takayuki, Anders, Hans‐J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293176/
https://ncbi.nlm.nih.gov/pubmed/30564368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.450
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