Cytoresistance after acute kidney injury is limited to the recovery period of proximal tubule integrity and possibly involves Hippo‐YAP signaling

Rat proximal tubule (PT) cells that have recovered from severe acute kidney injury induced by uranyl acetate (UA) develop cytoresistance to subsequent UA treatments. We reported that enhanced G1 arrest might contribute to cytoresistance. Herein, we examined these mechanisms by investigating Yes‐asso...

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Bibliographic Details
Published in:Physiol Rep
Main Authors: Iwakura, Takamasa, Fujigaki, Yoshihide, Fujikura, Tomoyuki, Tsuji, Takayuki, Ohashi, Naro, Kato, Akihiko, Yasuda, Hideo
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471447/
https://ncbi.nlm.nih.gov/pubmed/28611154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13310
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