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Role of Mitochondrial DNA in Septic AKI via Toll-Like Receptor 9

Toll-like receptor 9 (TLR9) contributes to the development of polymicrobial septic AKI. However, the mechanisms that activate the TLR9 pathway and cause kidney injury during sepsis remain unknown. To determine the role of mitochondrial DNA (mtDNA) in TLR9-associated septic AKI, we established a ceca...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Tsuji, Naoko, Tsuji, Takayuki, Ohashi, Naro, Kato, Akihiko, Fujigaki, Yoshihide, Yasuda, Hideo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926971/
https://ncbi.nlm.nih.gov/pubmed/26574043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015040376
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