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Role of Mitochondrial DNA in Septic AKI via Toll-Like Receptor 9

Toll-like receptor 9 (TLR9) contributes to the development of polymicrobial septic AKI. However, the mechanisms that activate the TLR9 pathway and cause kidney injury during sepsis remain unknown. To determine the role of mitochondrial DNA (mtDNA) in TLR9-associated septic AKI, we established a ceca...

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Bibliografski detalji
Izdano u:J Am Soc Nephrol
Glavni autori: Tsuji, Naoko, Tsuji, Takayuki, Ohashi, Naro, Kato, Akihiko, Fujigaki, Yoshihide, Yasuda, Hideo
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926971/
https://ncbi.nlm.nih.gov/pubmed/26574043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015040376
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