MDM2 inhibitor ameliorates cisplatin‐induced nephropathy via NFκΒ signal inhibition

Cisplatin is a platinum‐containing chemotherapeutic drug, which is widely used and highly effective. While effective against tumors, its use is limited by severe side effects such as nephrotoxicity and bone marrow suppression. Murine double minute 2 (MDM2) is the E3 ubiquitin ligase of the tumor sup...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Pharmacol Res Perspect
Main Authors: Fujikura, Tomoyuki, Yasuda, Hideo, Iwakura, Takamasa, Tsuji, Takayuki, Anders, Hans‐J.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293176/
https://ncbi.nlm.nih.gov/pubmed/30564368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.450
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker