Celastrol ameliorates cisplatin nephrotoxicity by inhibiting NF-κB and improving mitochondrial function

BACKGROUND: Celastrol is an active ingredient of Chinese medicine Tripterygium wilfordii which is clinically used to treat the immune diseases. Currently, celastrol is documented as a potent agent for treating cancer and inflammatory disorders. This study was to investigate the effect of celastrol o...

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Spremljeno u:
Bibliografski detalji
Izdano u:EBioMedicine
Glavni autori: Yu, Xiaowen, Meng, Xia, Xu, Man, Zhang, Xuejuan, Zhang, Yue, Ding, Guixia, Huang, Songming, Zhang, Aihua, Jia, Zhanjun
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2018
Teme:
Research paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197337/
https://ncbi.nlm.nih.gov/pubmed/30268831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.09.031
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