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Inhibition of Mitochondrial Complex-1 Prevents the Downregulation of NKCC2 and ENaCα in Obstructive Kidney Disease

Ureteral obstruction with subsequent hydronephrosis is a common clinical complication. Downregulation of renal sodium transporters in obstructed kidneys could contribute to impaired urinary concentrating capability and salt waste following the release of a ureteral obstruction. The current study was...

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Pubblicato in:Sci Rep
Autori principali: Zhang, Yue, Sun, Ying, Ding, Guixia, Huang, Songming, Zhang, Aihua, Jia, Zhanjun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513566/
https://ncbi.nlm.nih.gov/pubmed/26207612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12480
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