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MnTBAP therapy attenuates the downregulation of sodium transporters in obstructive kidney disease

Ureteral obstruction is associated with reduced expressions of renal sodium transporters, which contributes to impaired urinary concentrating capacity. In this study, we employed a synthetic mitochondrial superoxide dismutase 2 (SOD2) mimic MnTBAP to investigate the role of mitochondrial oxidative s...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Mi, Zhu, Yangyang, Sun, Ying, Wen, Zhaoying, Huang, Songming, Ding, Guixia, Zhang, Aihua, Jia, Zhanjun, Zhang, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787475/
https://ncbi.nlm.nih.gov/pubmed/29416622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23037
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