Rotenone Remarkably Attenuates Oxidative Stress, Inflammation, and Fibrosis in Chronic Obstructive Uropathy

Mitochondrial abnormality has been shown in many kidney disease models. However, its role in the pathogenesis of chronic kidney diseases (CKDs) is still uncertain. In present study, a mitochondrial complex I inhibitor rotenone was applied to the mice subjected to unilateral ureteral obstruction (UUO...

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Detalhes bibliográficos
Main Authors: Sun, Ying, Zhang, Yue, Zhao, Daqiang, Ding, Guixia, Huang, Songming, Zhang, Aihua, Jia, Zhanjun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130131/
https://ncbi.nlm.nih.gov/pubmed/25140114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/670106
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