Rotenone Remarkably Attenuates Oxidative Stress, Inflammation, and Fibrosis in Chronic Obstructive Uropathy

Mitochondrial abnormality has been shown in many kidney disease models. However, its role in the pathogenesis of chronic kidney diseases (CKDs) is still uncertain. In present study, a mitochondrial complex I inhibitor rotenone was applied to the mice subjected to unilateral ureteral obstruction (UUO...

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Autors principals: Sun, Ying, Zhang, Yue, Zhao, Daqiang, Ding, Guixia, Huang, Songming, Zhang, Aihua, Jia, Zhanjun
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130131/
https://ncbi.nlm.nih.gov/pubmed/25140114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/670106
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