Inhibition of COX-2/PGE2 cascade ameliorates cisplatin-induced mesangial cell apoptosis

Cisplatin is one of the most potent cytotoxic drug for the treatment of many types of cancer. However, the side effects on normal tissues, particularly on the kidney, greatly limited its use in clinic. Emerging evidence demonstrated that cisplatin could directly cause mesangial cell apoptosis, while...

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Vydáno v:Am J Transl Res
Hlavní autoři: Yu, Xiaowen, Yang, Yunwen, Yuan, Hui, Wu, Meng, Li, Shuzhen, Gong, Wei, Yu, Jing, Xia, Weiwei, Zhang, Yue, Ding, Guixia, Huang, Songming, Jia, Zhanjun, Zhang, Aihua
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376013/
https://ncbi.nlm.nih.gov/pubmed/28386348
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