Inhibition of COX-2/PGE2 cascade ameliorates cisplatin-induced mesangial cell apoptosis

Cisplatin is one of the most potent cytotoxic drug for the treatment of many types of cancer. However, the side effects on normal tissues, particularly on the kidney, greatly limited its use in clinic. Emerging evidence demonstrated that cisplatin could directly cause mesangial cell apoptosis, while...

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Publicat a:Am J Transl Res
Autors principals: Yu, Xiaowen, Yang, Yunwen, Yuan, Hui, Wu, Meng, Li, Shuzhen, Gong, Wei, Yu, Jing, Xia, Weiwei, Zhang, Yue, Ding, Guixia, Huang, Songming, Jia, Zhanjun, Zhang, Aihua
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376013/
https://ncbi.nlm.nih.gov/pubmed/28386348
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