COX-2/mPGES-1/PGE(2) cascade activation mediates uric acid-induced mesangial cell proliferation

Hyperuricemia is not only the main feature of gout but also a cause of gout-related organ injuries including glomerular hypertrophy and sclerosis. Uric acid (UA) has been proven to directly cause mesangial cell (MC) proliferation with elusive mechanisms. The present study was undertaken to examined...

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發表在:Oncotarget
Main Authors: Li, Shuzhen, Sun, Zhenzhen, Zhang, Yue, Ruan, Yuan, Chen, Qiuxia, Gong, Wei, Yu, Jing, Xia, Weiwei, He, John Ci-Jiang, Huang, Songming, Zhang, Aihua, Ding, Guixia, Jia, Zhanjun
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2016
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354651/
https://ncbi.nlm.nih.gov/pubmed/28052039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14363
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