Mitochondrial oxidative stress activates COX-2/mPGES-1/PGE2 cascade induced by albumin in renal proximal tubular cells

COX-2/mPGES-1/PGE2 cascade is of importance in the pathogenesis of kidney injury. Meanwhile, recent studies documented a detrimental role of mitochondrial oxidative stress in kidney diseases. The present study was undertaken to investigate the role of mitochondrial oxidative stress in albumin-induce...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Zhuang, Yibo, Wang, Chenhu, Wu, Chunfeng, Ding, Dan, Zhao, Fei, Hu, Caiyu, Gong, Wei, Ding, Guixia, Zhang, Yue, Chen, Lihong, Yang, Guangrui, Zhu, Chunhua, Zhang, Aihua, Jia, Zhanjun, Huang, Songming
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823666/
https://ncbi.nlm.nih.gov/pubmed/29507686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24187
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