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Role of Herpes Simplex Virus Type 1 (HSV-1) Glycoprotein K (gK) Pathogenic CD8(+) T Cells in Exacerbation of Eye Disease

HSV-1-induced corneal scarring (CS), also broadly referred to as Herpes Stromal Keratitis (HSK), is the leading cause of infectious blindness in developed countries. It is well-established that HSK is in fact an immunopathological disease. The contribution of the potentially harmful T cell effectors...

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Pubblicato in:Front Immunol
Autori principali: Jaggi, Ujjaldeep, Wang, Shaohui, Tormanen, Kati, Matundan, Harry, Ljubimov, Alexander V., Ghiasi, Homayon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292954/
https://ncbi.nlm.nih.gov/pubmed/30581441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02895
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