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CD80 Plays a Critical Role in Increased Inflammatory Responses in Herpes Simplex Virus 1-Infected Mouse Corneas

We recently reported that herpes simplex virus 1 (HSV-1) infection suppresses CD80 but not CD86 expression in vitro and in vivo. This suppression required the HSV-1 ICP22 gene. We also reported that overexpression of CD80 by HSV-1 exacerbated corneal scarring in BALB/c mice. We now show that this re...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Tormanen, Kati, Wang, Shaohui, Ghiasi, Homayon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955247/
https://ncbi.nlm.nih.gov/pubmed/31619558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01511-19
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