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A transient DMSO treatment increases the differentiation potential of human pluripotent stem cells through the Rb family
The propensity for differentiation varies substantially across human pluripotent stem cell (hPSC) lines, greatly restricting the use of hPSCs for cell replacement therapy or disease modeling. Here, we investigate the underlying mechanisms and demonstrate that activation of the retinoblastoma (Rb) pa...
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| Опубликовано в: : | PLoS One |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6291069/ https://ncbi.nlm.nih.gov/pubmed/30540809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208110 |
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