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A simple tool to improve pluripotent stem cell differentiation
We develop a method to overcome previously documented restrictions on the differentiation propensities of pluripotent stem cells. Culturing pluripotent stem cells in dimethylsulfoxide (DMSO) activates the retinoblastoma protein, increases the proportion of cells in the early G1 phase of the cell cyc...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3694177/ https://ncbi.nlm.nih.gov/pubmed/23584186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2442 |
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